School of Dentistry


Minnesota Dental Research Center for Biomaterials and Biomechanics


Nanocomposites and tissue engineering

MDRCBB has a major research effort in the development of Calcium Hydroxy Apatite/ Collagen nanocomposites as bone and dental hard tissue replacements. This research effort was headed by Dr. Ching-Chang Ko (now of the University of North Carolina) and Dr. Myung C. Chang. This work uses biomimetic processes to produce nanocomposites, which may offer novel properties and remineralization potential, as well as serve as scaffolding for the deposition of natural tissues in situ. The technology uses gated filters and pH controlled feedback pumps to create a benign biological environment favorable to the precipitation of highly calcified structures.


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  • Last modified on August 29, 2012