Isha Mutreja, PhD, MSc

Research Assistant Professor, School of Dentistry

PhD, Biomedical Engineering, Ulster University (United Kingdom)

MSc, Nanoscience, Amity University (India)



Research Funding Grants

Department of Defense (PROP 2019); ‘‘Bioinspired Acellular Strategies to Optimize the Skin-Implant Interface of Osseointegrated Devices”; ($749,999) [Key Personnel]

University of Otago Research Grant Application (UORG 2017); ''3D breast tumor models for drug discovery; ($36684) [Named Investigator]

COE Strategic Research Grant 2014; ($3000) [PI and Principal Researcher]

Biomolecular Interaction Centre Flagship collaborative grants; Osteogenic differentiation of stem cells using Bioimprinted Surfaces ($3000) [PI and Principal Researcher]


Adhesive for Osseointegrated Percutaneous Devicses (Provisional Patent Application submitted)


A novel methacrylate derivative polymer that resists bacterial cell mediated biodegradation, Dhiraj Kumar, Debarati Ghose, Isha Mutreja, Robert D Bolskar, and Robert S Jones. 2021 (Journal, DOI: Submitting). 

Strontium- and peptide-modified silicate nanostructures for dual osteogenic and antimicrobial activity, Isha Mutreja, Dhiraj Kumar, Kami Hogan, Emily Campbell, Kim Mansky, Conrado Aparicio. 2021 (Journal, DOI: Submitting). 

Esterase biodegradation resistance by using a flipped external ester group within a novel methacrylate derivative polymer, Dhiraj Kumar, Debarati Ghose, Robert D Bolskar, Isha Mutreja, Conrado Aparicio, and Robert S Jones. 2021 (Acta Biomaterialia, DOI: Submitted). 

Biomimetic mineralized hybrid scaffolds with antimicrobial peptides. Z Ye, X Zhu, I Mutreja, S Boda, N G Ficher, A Zhang, C Lui, Y Qi and C Aparicio, Bioactive Materials 2021, 6(8): 2250-2260 

A Novel Dental Polymer with a Flipped External Ester Group Design that Resists Degradation via Polymer Backbone Preservation. D Kumar, R D Bolskar, S Malone, I Mutreja, C Aparicio and R S Jones, ACS Biomaterials and Engineering 2020, 6(10): 5609-5619 

Cell responses to titanium and titanium alloys. I Mutreja, Z Ye, C Aparicio, Woodhead Publishing Series in Biomaterials, Handbook of Biomaterials Biocompatibility, imprint of Elseviers, edited by Masoud Mozafari, 2020: 423-452 [ISBN 9780081029671] 

Combined Infection Control and Enhanced Osteogenic Differentiation Capacity on Additive Manufactured Ti-6Al-4V are Mediated via Titania Nanotube Delivery of Novel Biofilm Inhibitors. J Li, I Mutreja, G J Hooper, K Clinch, K S Lim, GB Evans and T B F Woodfield, Advanced Material Interfaces 2020, 7(7): 1901963 (cited – 6) 

Design and characterisation of multi-functional strontium-gelatin nanocomposite bioinks with improved print fidelity and osteogenic capacity. C R Alcala-Orozco, I Mutreja, X Cui, D Kumar, G J Hooper, K S Lim, T B F Woodfield, Bioprinting 2020 18, e00073 (cited – 16) 

Hydrodynamic control of titania nanotube formation on Ti-6Al-4V alloys enhances osteogenic differentiation of human mesenchymal stromal cells. J Li, I Mutreja, S Tredinnick, M Jermy, G J Hooper, T B F Woodfield, Materials Science and Engineering: C 2020 109, 110562 (cited – 7) 

Orthopaedic Osseointegration: Implantology and Future Directions. A L Overmann, C Aparicio, J T Richards, I Mutreja, N G Fischer, S M Wade, B K Potter, T A Davis, J E Bechtold, J A Forsberg, D Dey; Journal of Orthopaedic Research 2019 38(7):1445-1454 (cited – 14) 

Osteogenic and angiogenic tissue formation in high fidelity nanocomposite Laponitegelatin bioinks. G Cidonio, C R Alcala-Orozco, K S Lim, M Glinka, I Mutreja, Y Kim, J I Dawson, T B F Woodfield, R Oreffo; Biofabrication 2019, 11(3) (cited – 47) 

Biofilm inhibition via delivery of novel methylthioadenosine nucleosidase inhibitors from PVA-tyramine hydrogels while supporting mesenchymal stromal cell viability. I Mutreja, S L Warring, K S Lim, T Swadi, K Clinch, J M Mason, C R Sheen, D R Thompson, R G Ducati, S T Chambers, G B Evans, M L Gerth, A G Miller, T B F Woodfield; ACS Biomaterials and Engineering 2018, 5(2): 748 (cited – 5) 

Automated 3D bioassembly of micro-tissues for biofabrication of hybrid tissue engineered constructs. N V Mekhileri, K S Lim, G C J Brown, I Mutreja, B S Schon, G J Hooper, T B F Woodfield; Biofabrication 2018, 10(2): 4103 (cited – 83) 

Cytotoxicity and cellular uptake of different sized gold nanoparticles in ovarian cancer cells, D Kumar, I Mutreja, K Chitcholtan, P Sykes; Nanotechnology, 2017, 28(47):p475101 (cited – 24) 

Seed mediated synthesis of highly mono-dispersed gold nanoparticles in presence of hydroquinone, D Kumar, I Mutreja, P Sykes; Nanotechnology, 2016, 27(35):p. 355601 (cited – 17) 

Fabrication of free-standing casein devices with micro- and nanostructured regular and bioimprinted surface features, A Hashemi, I Mutreja, M M Alkaisi, V Nock, A M Ali; Journal of Vacuum Science and Technology B, 2015, 33:p. 06F901 (cited – 6) 

ORMOSIL nanoparticle Interaction with Macrophage Cells: Assessment of Cell Viability on the Basis of Physico-Chemical Properties of Nanoparticles, D Kumar, I Mutreja, P C Keshvan, M Bhat, A K Dinda, S Mitra; Journal of Pharmaceutical Science, 2015, 104(11):p. 3943-3951 (cited – 11) 

Positive and negative bioimprinted polymeric substrates: new platforms for cell culture, I Mutreja, S Sperling, T B F Woodfield, J J Evans, M M Alkaisi; Biofabrication, 2015,7(2):p. 025002 (cited – 24) 

The Deposition of Strontium-Substituted Hydroxyapatite Coatings, A R Boyd, L Rutledge, I Mutreja, L D Randolph, B J Meenan; Journal of Materials Science: Materials in Medicine, Pharmaceutical Science, 2015, 26(2):p. 65 (cited – 37) 

Enamel proteins mitigate mechanical and structural degradations in mature human enamel during acid attack, G V Lubarsky, P Lemoine, B J Meenan, S Deb, I Mutreja, P Carolan, N Petkov; Materials Research Express, 2014, 1(2) (cited – 12) 

The profile of payload release from gold nanoparticles modified with a BODIPY®/PEG mixed Monolayer, D Kumar, I Mutreja, B J Meenan, D Dixon, Journal of Nano Research, 2013, 25, 16-30 (cited – 6) 

Titania Nanotube Porosity Controls Dissolution Rate of Sputter Deposited Calcium Phosphate (CaP) Thin Film Coatings, I Mutreja, D Kumar, A Boyd and BJ Meenan; RSC Advances, 2013. 3:p. 11263-11273 (cited – 10) 

Controlling the Size and Size Distribution of Gold Nanoparticles: A Design of Experiment Study, D Kumar, B J Meenan, I Mutreja, R D’Sa, D Dixon; International Journal of Nanoscience, 2012. 11:p.1250023-1250030 (cited – 37) 

Modulation of physiochemical properties of Chitosan Nanoparticles prepared by Ionic Gelation and Micro-Emulsion methods, V K Sharma, I Mutreja, S Mitra; International Journal of Nanoscience, 2009. 8:p.191 (cited – 2)