Todd Doran, PhD

Assistant Professor, Department of Medicinal Chemistry

Todd Doran

Contact Info

doran@umn.edu

Office Phone 612-625-9335

Office Address:
8-123 Weaver-Densford Hall

Mailing Address:
University of Minnesota
Department of Medicinal Chemistry
8-101 Weaver Densford Hall
308 Harvard Street S.E.
Minneapolis, MN 55455

Assistant Professor, Department of Medicinal Chemistry

Institute for Translational Neuroscience Scholar


Post-Doc, The Scripps Research Institute

PhD, University of Rochester

Summary

The Doran Lab

We are a multi-disciplinary laboratory interested in understanding the molecular-level events that underlie neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Our long-term goals are to diagnose and stop disease progression using novel chemical and biological molecules. We welcome trainees interested in all aspects of chemistry and biology who wish to help us realize our goals. Please visit our laboratory website to learn more about our chemical biology program.

Expertise

Diagnostic imaging, immunotherapeutics, organic synthesis, high-throughput screening

Research

Research Summary/Interests

We have three research projects that aim to better understand molecular mechanisms of neurodegeneration. The goals of these projects are to 

1. Characterize and exploit the adaptive immune response during Alzheimer’s and Parkinson’s disease. 

2. Develop small molecule probes for intractable pre-amyloid oligomers for imaging agents. 

3. Clarify the role of neurotransmitters and pigment aggregates during aging and neurodegeneration.

Publications